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By Sabine Walter, Pierre A. What makes women different from men is that much of our sexual apparatus is on the inside — most notably, the vagina. The vagina itself is a hollow, muscular tube that extends from the external opening at the vestibule all the way to the cervix. The walls of the vagina have several layers: the mucosa, which secretes various fluids; a muscular layer; and connective tissue. Beneath the vagina, on the pelvic floor, are other muscles that are responsible for keeping the vagina elevated, tight, and firm.

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The development of the reproductive systems begins soon after fertilization of the egg, with primordial gonads beginning to develop approximately one month after conception. Reproductive development continues in utero, but there is little change in the reproductive system between infancy and puberty. To become a male, an individual must be exposed to the cascade of factors initiated by a single gene on the male Y chromosome. Because females do not have a Y chromosome, they do not have the SRY gene. Without a functional SRY gene, an individual will be female.

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What is the clitoris? And where is it?

In men and women sexual arousal culminates in orgasm, with female orgasm solely from sexual intercourse often regarded as a unique feature of human sexuality. However, orgasm from sexual intercourse occurs more reliably in men than in women likely reflecting the different types of physical stimulation men and women require for orgasm. In men, orgasms are under strong selective pressure as orgasms are coupled with ejaculation and thus contribute to male reproductive success. By contrast, women's orgasms in intercourse are highly variable and are under little selective pressure as they are not a reproductive necessity. The proximal mechanisms producing variability in women's orgasms are little understood.

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